Try a synonym, or sign up to suggest a template from the app.
BioRender Template
Senescence Associated Secretory Phenotype (SASP)
Description
External stimuli, damage or stress from physiological insults, reactive oxidative species (ROS), radiation, and nutrient deprivation can activate multi-step intracellular signalling cascades that lead to epigenomic modifications or genomic damage. In turn, the genomic instability leads to irreversible cell cycle arrest, metabolic changes, lysosomal accumulation, chromatin remodelling, and a proinflammatory secretome, otherwise known as the senescence-associated secretory phenotype (SASP).
Use this templateThis template is fully editable in BioRender with a free BioRender account — no credit card required to sign up.
Don’t start from scratch.
Create professional scientific illustrations quickly and easily, even without any design expertise
- Get started with a huge library of editable icons and templates such as common biological pathways, anatomy, or genetics.
- Create figures that effectively communicate your research in half the time using our editable icons.
- Use our PDB tool to quickly generate and customize protein structures.
.gif)




